Sunday, September 5, 1999
| 07.30 - 08.30 | Clinical Conference T5 | AUDITORIUM 1 |
| THE CHILD WITH ELECTROLYTE DISTURBANCE J. Rodriguez-Soriano (Spain) E. Sulyok (Hungary) |
Three interesting patients with hypercalciuria will be presented and discussed with the audience.The first patient is a 2 year-old boy presenting with hyponatremic dehydration and hypercalciuria; the second patient is a newborn infant having at birth a picture that mimics primary peudohypoaldosteronism with nephrocalcinosis; and the third patient is a 10 year-old boy suffering from general malaise, fever, hypercalciemia, hypercalciuria, nephrocalcinosis and nephrolithiasis. In each case data will be given in a progressive fashion to allow for an open discussion before diagnosis is made. At the end of the discussion pertinent bibliography will be provided.
| 07.30 - 08.30 | Clinical Conference T6 | AUDITORIUM 2 |
| CLINICO-PATHOLOGICAL CONFERENCE P. Niaudet (France) R. Waldherr (Germany) |
In this conference clinical and pathological aspects (biopsy findings) will be discussed in three children with special renal diseases. Particular attention will be given to differential diagnosis and recent advances in treatment, pathogenesis and prognosis. Audience participation is specifically encouraged.
| 08.35 - 09.15 | State of the Art Lecture L5 | AUDITORIUM 1 |
| THE ROLE OF AQUAPORINES IN URINE CONCENTRATION C. van Os (The Netherlands) Chairperson: M. Brandis (Germany) |
| 09.15 - 10.45 | Free Communications V. | AUDITORIUM 1 |
| RENAL TRANSPLANTATION Chairperson: C. Loirat (France), J. Dušek (Czech Republic) |
| 09.15 - 09.40 | |
| ** Invited Lecture ** | THROMBOPHILIA IS A RISK FACTOR FOR EARLY LOSS OF RENAL ALLOGRAFTS F.R. Green (United Kingdom) |
| 09.40 - 09.53 | |
| O21 | LONG-TERM RENAL FUNCTION IS DETERMINED BY AGE IN SMALL CHILDREN E. Qvist, L. Krogerus, J. Laine, H. Jalanko, K. Rönnholm, C. Holmberg (Finland) |
| 09.53 - 10.06 | |
| O22 | NF-kB GENE ACTIVATION IN ACUTE REJECTION AND TREATMENT REFRACTORY
NEPHROTIC LESIONS INDICATES INEFFECTIVE BLOCKING OF CYTOTOXIC MEDIATOR J. Strehlau, C. v. Schnakenburg, A.D. Schachter, A. Strasburg, G. Offner, K. Latta, B. Enke, G. Filler, J.H.H. Ehrich (Germany) |
| 10.06 - 10.19 | |
| O23 | MODULATION OF NITRIC OXIDE SYNTHASE ACTIVITY AND APOPTOSIS IN
ENDOTHELIAL CELLS: COMPARISON BETWEEN CYCLOSPORIN (CyA), FK506 AND MOFETIL MYCOPHENOLATE
(MMF) G. Conti, A. Amore, P. Cirina, R. Coppo (Italy) |
| 10.19 - 10.32 | |
| O24 | PHARMACOKINETIC-PHARMACODYNAMIC RELATIONSHIPS OF TOTAL AND FREE
MYCOPHENOLIC ADIC (MPA) IN PEDIATRIC RENAL TRANSPLANT RECIPIENTS L.T. Weber, A. Staskewitz, N. Wagner, M. Shipkova, O. Mehls, L.B. Zimmerhackl, V.W. Armstrong, B. Tönshoff and the German Study Group on MMF Therapy (Germany) |
| 10.32 - 10.45 | |
| O25 | DISPOSITION OF BASILIXIMAB IN DE NOVO PEDIATRIC RENAL TRANSPLANTATION G. Offner, P. Broyer, C. Loirat, M. Mentser, J. Lamire, J. Crocker, P. Cochat, G. Clark, C. Gerbeau, M. Hall, J. Kovarik (Switzerland) |
| 09.15 - 10.45 | Free Communications VI. | AUDITORIUM 2 |
| MOLECULAR GENETICS Chairperson: F. Hildebrandt (Germany), M.C. Gubler (France) |
| 09.15 - 09.28 | |
| O26 | NPHS1 GENE MUTATIONS IN FINNISH TYPE CONGENITAL NEPHROTIC SYNDROME
PATIENTS OF NON-FINNISH ORIGIN A. Koziell, U. Lenkkeri, V. Grech, S. Ozen, R.S. Trompeter, T.M. Barratt, K. Tryggvason, P. Scambler (UK) |
| 09.28 - 09.41 | |
| O27 | GENOTYPE-PHENOTYPE CORRELATION IN TURKISH PATIENTS WITH FAMILIAL
MEDITERRANEAN FEVER F. Yalcinkaya, N. Cakar, M. Misirhoglu, N. Tümer, N. Akar, M. Tekin, H. Tastan, H. Kocak, N. Özkaya (Turkey) |
| 09.41 - 09.54 | |
| O28 | IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF THREE NOVEL MISSENSE
MUTATIONS FOUND IN PATIENTS WITH NEPHROGENIC DIABETES INSIPIDUS K. Pasel, A. Schulz, K. Timmermann, M. Hoelzenbein, J. Jääskeläinen, G. Filler, T. Schöneberg (Germany) |
| 09.54 - 10.07 | |
| O29 | PAX-2 EXPRESSION IN JUVENILE NEPHRONOPHTHISIS L. Murer, G.M. Ghiggeri, M. Della Vella, G. Montini, G. Caridi, R. Dall´Amico, B. Andreetta, G. Zacchello (Italy) |
| 10.07 - 10.20 | |
| O30 | CLINICAL, MORPHOLOGICAL AND GENETIC CHARACTERIZATION OF A NOVEL TYPE OF
NEPHRONOPHTHISIS: ADOLESCENT NEPHRONOPHTHISIS MAPS TO 3q22 H. Omran, C. Fernandez, M. Jung, K. Häffner, B. Fargier, F. Rüschendorf, N. Gretz, R. Waldherr, A. Reis, M. Brandis, F. Hildebrandt (Germany) |
| 10.20 - 10.45 | |
| ** Invited Lecture ** | NOVEL MUTATIONS IN THE RENAL POTASSIUM CHANNEL ROMK CAUSING
HYPERPROSTAGLANDIN E SYNDROME: FUNCTIONAL STUDIES IN XENOPUS OOCYTES M. Konrad (Germany) |
| 10.45 - 11.15 | Coffee Break |
| 11.15 - 12.45 | Free Communications VII. | AUDITORIUM 1 |
| GLOMERULAR DISORDERS Chairperson: R. Coppo (Italy), K. Schärer (Germany) |
| 11.15 - 11.28 | |
| O31 | RENAL FUNCTION AND MORPHOLOGY IN PAN INDUCED NEPHROTIC SYNDROME IN RATS E. Löwenborg, G. Jaremko, U. Berg (Sweden) |
| 11.28 - 11.41 | |
| O32 | THE ROLE OF NO AND APOPTOSIS IN ADR INDUCED NEPHROSIS: THE EFFECT OF
iNOS INHIBITION Y. Usta, S. Ozen, U. Saatci, A. Bakkaloglu, d. Orhon, B. Yang, N. Besbas, R. Topaloglu, O. Tulunay, I. Erdemli, A.M. El-Nahas (Turkey) |
| 11.41 - 11.54 | |
| O33 | WT1 SPLICE-SITE MUTATION CAN BE INVOLVED IN STEROID-RESISTANT FOCAL AND
SEGMENTAL GLOMERULAR SCLEROSIS (FSGS). C. Loirat, E. Denamur, N. Bocquet, V. Baudouin, M. Peuchmaur, J. Elion (France) |
| 11.54 - 12.07 | |
| O34 | IS ERYTHROPOIETIN (EPO) DEFICIENCY A CAUSE OF ANEMIA IN NEPHROTIC
PATIENTS WITH NORMAL KIDNEY FUNCTION? S. Feinstein, N. Algur, R. Becker-Cohen, Y. Frishberg (Israel) |
| 12.07 - 12.20 | |
| O35 | MANAGEMENT OF CONGENITAL NEPHROTIC SYNDROME L. Kovacevic, C.J.D. Reid (UK) |
| 12.20 - 12.33 | |
| O36 | RESULTS OF THE NEPHROTIC SYNDROME STUDY VIII OF THE APN: NEW STANDARD
TREATMENT VERSUS NEW STANDARD TREATMENT PLUS 8 WEEKS CYCLOSPORIN A P.F. Hoyer (Germany) |
| 12.33 - 12.45 | |
| O37 | ARTERIO-VENOUS FISTULAS AFTER PERCUTANEOUS RENAL BIOPSY IN CHILDREN:
IMAGING AND MANAGEMENT P. Schmit, N. Sayegh, F. Brunelle, P. Niaudet (France) |
| 11.15 - 12.45 | Free Communications VIII. | AUDITORIUM 2 |
| TUBULAR DISORDERS Chairperson: ???, H.W. Seyberth (Germany) |
| 11.15 - 11.28 | |
| O38 | NON-CLASSIFIED HYPEROXALURIAS: PRIMARY HYPEROXALURIA TYPE 3 (PH3) OR
ABSENCE OF OXALOBACTER? T.J. Neuhaus, N. Blau, B. Hoppe, H. Sidhu, E. Leumann (Switzerland) |
| 11.28 - 11.41 | |
| O39 | IGF-1 NORMALIZES THE RENAL PHOSPHATE LEAK IN HEREDITARY HYPERCALCIURIA
WITH RENAL HYPOPHOSPHATEMIA (HHRH) W. Proesmans, M. Van Dyck, C.B. Langman (Belgium) |
| 11.41 - 11.54 | |
| O40 | HEREDITARY ISOLATED RENAL MAGNESIUM LOSS MAPS TO CHROMOSOME 11q23 H. Meij, K. Saar, L. van den Heuvel, G. Neurnberg, M. Vollmer, F. Hildebrandt, A. Reis, L. Monnens, V. Knoers (The Netherlands) |
| 11.54 - 12.07 | |
| O41 | PHENOTYPE-GENOTYPE CORRELATIONS IN TWO SPANISH KINDRED WITH RENAL
PSEUDOHYPOALDOSTERONISM TYPE 1 A. Vallo, D.S. Geller, J. Rodríguez-Soriano, R.P. Lifton (Spain) |
| 12.07 - 12.20 | |
| O42 | EVIDENCE FOR GENETIC HETEROGENEITY OF GITELMAN SYNDROME N. Jeck, M. Konrad, M. Heß, S. Weber, S. Reinalter, H.W. Seyberth (Germany) |
| 12.20 - 12.33 | |
| O43 | A RARE ETIOLOGY OF PROXIMAL TUBULOPATHY: ARCC SYNDROME V. Baudouin, M.A. Macher, H. Ogier, C. Baumann, O. Fenneteau, C. Loirat (France) |
| 12.33 - 12.45 | |
| O44 | NEPHROCALCINOSIS IN PRETERM NEONATES: MODULATION OF CALCIUM OXALATE
CRYSTALLIZATION KINETICS BY URINE OF PRETERM NEONATES E.A. Shell-Feith, J.E. Kist-van Holthe, I. Que, S.E. Papapoulos, N. Conneman, R. Brand, A.J. van der Heijden (The Netherlands) |
| 12.45 - 13.15 | Lunch |
| 13.15 - 14.45 | Symposium S9 | AUDITORIUM 1 |
| NEPHROTIC SYNDROME: A PODOCYTE DISORDER? Chairman: C. Holmberg (Finland), ??? |
• STRUCTURE AND FUNCTION OF PODOCYTES - W. Kriz (Germany)
• PATHOGENESIS OF NEPHROSIS - S. Mir (Turkey)
• THE ROLE OF NEPHRIN IN NEPHROSIS - H. Jalanko (Finland)
| 13.15 - 14.45 | Symposium S10 | AUDITORIUM 2 |
| RENAL TRANSPLANTATION Chairperson: P. Cochat (France), Z. Puretic (Croatia) |
• LYMPHOPROLIFERATIVE DISEASES FOLLOWING RENAL TRANSPLANTATION - P.L. Amlot (United
Kingdom)
• POST-TRANSPLANT COURSE OF LIVER INVOLVEMENT IN HEREDITARY KIDNEY DISEASE - D. Kelly
(United Kingdom)
• REVIVAL OF INDUCTION THERAPY - J.P. Revillard (France)
| 14.45 - 15.00 | Closing remarks |